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Profile, screen, identify and quantify a wide variety of compounds with confidence
Our next generation Thermo Scientific LC-MS systems deliver on ease without sacrificing high performance. A unified instrument architecture enables same performance accessories between systems, facilitates easier method transfer, and accelerates familiarization for new users. Intelligence-driven systems enables the highest quality mass spectrometry data for increased confidence. Pre-defined experimental conditions enables more users to access and succeed. Streamlined data processing software, algorithms and libraries address the most challenging research and routine applications.
Browse our complete portfolio below, or let one of our experts help you tailor a selection specific to your application and workflow needs.
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Popular LC-MS products
Orbitrap Astral Mass Spectrometer
Orbitrap Eclipse Tribrid Mass Spectrometer
Orbitrap Exploris Mass Spectrometers
Featured LC-MS categories
Orbitrap LC-MS
Thermo Scientific Orbitrap mass spectrometers generate high-resolution and accurate-mass data, thereby enhancing sensitivity in trace analyte detection, characterization and quantitation, and comprehensive sample analysis.
Orbitrap Exploris LC-MS
Empowering translational research scientists to more extensively deploy MS for rigorous, high-throughput protein identification, quantitation and structural characterization the Thermo Scientific Orbitrap Exploris 480 MS combines proven technology, advanced capabilities and an intelligence-driven analytical framework.
Orbitrap Tribrid LC-MS
Push the limits of detection, characterization and quantitation with Thermo Scientific Orbitrap Tribrid Mass Spectrometers that enable multiple sophisticated modes of analysis.
Q Exactive Orbitrap LC-MS
Move from compound discovery into targeted quantitation for your sample type by choosing from a broad portfolio of Thermo Scientific Q Exactive Quadrupole-Orbitrap Mass Spectrometers.
Ion Trap LC-MS
For general purpose mass spectrometers, Ion trap mass spectrometers are cost-effective and can easily be operated by students learning the fundamentals of MS or for analytical applications.
Triple Quadrupole LC-MS
From achieving ultimate sensitivity requirements, robustness, reliability, and speed, triple quadrupole LC-MS systems help you address your challenges in routine, targeted quantitation for all molecule types.
Single Quadrupole LC-MS
These economical high-performance MS systems have the capacity to keep up with even the fastest UHPLC applications.
LC-MS Medical Devices
Comprehensive, reliable LC-MS platform solutions that enable clinical laboratories to achieve desired productivity and throughput goals, while ensuring confidence in results in laboratory developed tests (LDTs).
Online Sample Prep and Multichannel Systems
Online sample preparation and multichannel HPLC combine to lower per-sample costs while increasing sample throughout and data quality.
LC-MS Software
The right complement for our outstanding LC-MS systems, our software offers most comprehensive solution to data acquisition, processing, analysis, and reporting.
LC-MS Accessories
Optimize MS workflows and performance with a line of specialized ion sources, alternative dissociation techniques, probes that optimize MS workflows and performance to help you obtain the most sensitive data possible.
Chromatography
Choose from a variety of high quality Thermo Scientific chromatography consumables to meet your separation needs.
Ardia Platform
The Thermo Scientific Ardia Platform is a scalable software solution for modern environments. It connects and organizes projects, people, and instruments enabling scientists to get closer to the truth.
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Maximize your return on investment in a unified Thermo Scientific mass spectrometry architecture from data acquisition and analysis solutions
Thermo Scientific Orbitrap Astral Mass Spectrometer
Achieve faster throughput, deeper coverage, higher sensitivity with accurate and precise quantitation.
New! Introducing LC-MS Medical Devices for In Vitro Diagnostic Use
The new portfolio of Thermo Scientific LC-MS Medical Devices for laboratory developed tests offers the clinical laboratory six unique choices that meet a wide range of throughput and sensitivity needs.
Grant and Funding Central
From idea to reality
Need help with your grant writing? Get answers to your questions, access to valuable resources and the support you need to write a strong proposal.
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Featured applications
Environmental Emerging Contaminants
Our innovative techniques and instrumentation can help you keep pace with the identification and quantitation of emerging contaminants.
Biopharmaceutical Analytical Testing
Our advanced instrumentation and analytical workflows can help simplify the challenge of biopharmaceutical analysis.
Our high-performing instruments and software provide a high-level confidence in MS-based biomarker discovery and method development for biomarker verification.
Forensic Toxicology
Whether you need to screen and confirm known compounds, identify unknowns or advance forensic research, we offer a solution to meet your current and future needs.
Proteomics Mass Spectrometry
Our leadership is backed by state-of-the-art solutions in sample preparation, liquid chromatographic separations, mass spectrometry and proteomic software.
Metabolomics
Harness the power of metabolomics to gain in-depth biological insight, facilitate biomarker discovery, and advance scientific research.
Protein Structure Analysis with Mass Spectrometry
Explore multiple products and workflows for protein structure analysis plus learn more about integrative structural biology solutions that bring together mass spectrometry and cryo-electron microscopy.
Protein Analysis Sample Prep and Calibration
Our optimized kits, reagents and devices enable quick and easy sample preparation, protein quantitation, and instrument calibration.
Keep up with the speed of science
The Lab-Forward Trade-Up Program
The world needs science to move faster. Now more than ever. Which is why when more scientists have access to the latest scientific instrumentation, we all benefit. That is the sole purpose of our Lab-Forward Trade-Up Program. For a limited time, trade up your chromatography and mass spectrometry instruments and save!
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LC-MS webinar series
Expand your application knowledge
Our LC-MS on-demand webinar series expands your application knowledge for pharma, biopharma, environmental, omics, food, forensics and clinical research and more. Learn how the latest high-performance mass spectrometry solutions can enable your laboratory to solve your most pressing analytical challenges, regardless of sample type.
Affordability made easy
Interested in financing options, purchasing a factory-certified refurbished LC-MS instrument or trading-in your existing mass spectrometer for something better? Choose from a wide selection of high performance systems from the most routine, for all levels of experience, to the most sophisticated and advanced research. We can get you to greater productivity at an affordable price.
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Related Learning Centers More Learning Centers ›
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Resource Library › - LC-MS Information ›
- Mass SpectrometryApplication Areas ›
- Mass SpectrometryTechnology Overview ›
Resources
- LC-MS webinar series
- Mobile Lab Apps
- LC-MS Blog Posts
- Join Our Community
- Clinical Research and Forensic Toxicology Technical Handbook
- Poster Note: Method Development Considerations for Paper Spray Mass Spectrometry - Direct Ionization Technique for Physiological Fluid Analysis
- Grant Application Resource: Top 5 reasons to upgrade from a Hybrid Orbitrap to a Tribrid MS System
- White Paper: LC-MS Innovations: Review of the Technology and its Advancements
- Metabolomics Software Solutions
- Analytical and Life Science Webinar Library
Support
- Unity Lab Services
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